Matrixyl (Palmitoyl Pentapeptide-4)

Cosmetic / Research

Palmitoylated matrikine / collagen signaling peptide

Matrixyl (Palmitoyl Pentapeptide-4) is a lipopeptide that has been studied in dermatology research for its effects on collagen I, III, and IV synthesis, fibronectin, and hyaluronic acid production. Published research has investigated its role in extracellular matrix remodeling and skin structure maintenance. RaysunPeptide supplies Matrixyl for qualified research and laboratory applications.

Mechanism of Action

The KTTKS peptide fragment is associated with extracellular-matrix signaling, while palmitoylation improves lipid affinity and supports incorporation into topical formulations.

Key Benefits

1Supports collagen-related signaling research
2Widely studied for skin appearance
3Used in anti-aging cosmetic formulations
4Small five-amino-acid peptide
5Palmitoylation improves lipid compatibility

Molecular Data

Molecular Weight
802.1 Da
Half-Life
Not established as a systemic pharmacokinetic parameter
Chain Length
5 amino acids
Amino Acid Sequence
KTTKS

Research Indications

Skin

Photoaged Skinmoderate

Studied for potential improvement in the appearance of photoaged skin through collagen-related signaling.

Anti-Aging

Fine Lines and Wrinklesmoderate

Used in cosmetic research targeting the appearance of fine lines and wrinkles.

Extracellular Matrix

Collagen Signalingresearch

The KTTKS sequence is associated with signaling pathways involved in extracellular-matrix remodeling.

What to Expect

1
Weeks
Cosmetic changes, when present, generally develop gradually with continued topical use.
2
Months
Longer-term cosmetic effects depend on formulation, concentration and consistent application.

Side Effects & Safety

Common (Generally Mild)

  • •Possible mild skin irritation
  • •Redness
  • •Contact sensitivity

Stop Signs (Seek Medical Attention)

  • ⚠Severe irritation
  • ⚠Persistent dermatitis
  • ⚠Signs of allergic reaction

Contraindications

  • ✕Known sensitivity to the ingredient or formulation components

FAQs

What is Matrixyl?

Matrixyl commonly refers to palmitoyl pentapeptide-4, a palmitoylated peptide based on the KTTKS sequence and used primarily in cosmetic formulations.

What is the Matrixyl sequence?

The peptide portion is KTTKS: Lys-Thr-Thr-Lys-Ser.

Matrixyl (Palmitoyl Pentapeptide-4)

Specifications

Purity≥98% (HPLC verified)
FormLyophilized powder
Packaging10mg
StorageStore at -20°C, protect from light
Catalog No.MA10

Available Sizes

10mg$22